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Dr. Stephen A. Duncan

SmartState Endowed Chair in Regenerative Medicine

Regenerative Medicine

  • Postdoctoral Fellowship at the Rockefeller University
  • Ph.D. from Oxford University

Research in the Duncan Lab focuses on the
use of mice and stem cells to understand the contribution of transcription factors to embryonic development and function of the liver, pancreas, and heart. In addition, the
group has developed technologies to control the differentiation of stem cells into cells with hepatocyte (liver cell) characteristics.  In addition to using such cells to understand liver development, he is also using them to model inborn errors in liver metabolism and as a platform for drug discovery.

Dr. Duncan received his
PhD for working on vaccinia virus with Dr Geoffrey Smith, initially at Cambridge University, and completed it at Oxford University in 1992. He then moved to Rockefeller University in New
York City to undertake a postdoctoral fellowship in the laboratory of Dr James Darnell. This was completed in 1996 after which he became an Assistant Professor at the Rockefeller University. He moved to the Medical College of Wisconsin, Milwaukee in 1997, where, after moving through the ranks, he became a Professor of Cell Biology, Neurobiology and Anatomy. In 2007 he became the founding Director of MCW’s Program in Regenerative Medicine and the Marcus Professor of Human and Molecular Genetics. In 2015 Dr. Duncan relocated to the Medical University of South Carolina in Charleston, where he is currently the Chair of the Department of Regenerative Medicine and Cell Biology.

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