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Effectiveness Research in Orthopedics (CERotho)

Center of Economic Excellence



Award Amount

$5 million

External Funding Above Match

$16.2 Million

Research Focus

Medical health needs in ortopaedic disorders, exercise and sports-related injury prevention, treatment, and rehabilitation. The Center investigates the biologics of tissue-engineered materials and implantable devices to find solutions to musculoskeletal maladies.

University Partner

University of South Carolina

Private Sector Partner

Smith & Nephew

This Center conducts research in tissue-engineered materials and implantable devices that will help the thousands of people who suffer from orthopedic maladies each year. Research and clinical activities center on new materials to optimize rehabilitation and reconstruction of damaged joints caused by orthopedic disorders and exercise- and sports-related injuries. The Center’s research focus includes cellular engineering, rehabilitation and performance sciences, epidemiology and clinical translation, and education in the rehabilitation field.

The Center complements several of the University of South Carolina’s existing strengths, including its nationally prominent exercise science and bioengineering programs.
Center partners include Smith and Nephew, a global leader in the development and marketing of medical devices. In 2009, Smith & Nephew announced a $5 million non-state match for this Center. Because of its partnership with this Center, Smith & Nephew has created a fifth unit of its company, the Biologics & Spine Division, which develops cutting-edge orthopedic therapies and technologies.

Steadman Hawkins Clinic of the Carolinas and the Orthopaedic Research Foundation of the Carolinas serve as the clinical and educational practice partners for this Center.
The Center will create a clinical translational database to track the success of differing treatments, surgical outcomes and rehabilitation.

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