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Proteomics

Center of Economic Excellence

Inception

2003

Award Amount

$4 million

External Funding Above Match

$22.5 Million

Research Focus

Develop and use high-end analytical technologies to understand the biologic profile of protein expression in health and disease. Developing enzyme-based analytical methods to effectively detect biomolecules in tissues and tissue microarray platforms.

University Partner

Medical University of South Carolina (MUSC)

Private Sector Partner

Multiple Industry Partners

The Proteomics Center pursues research in technologies that study and gather information encoded in the genomes of proteins. Because of technology limitations, only limited protein information can currently be accessed and analyzed. However, the field of proteomics research is expected to lead to an understanding of cellular function at the molecular level, particularly how cellular functions go awry in disease. Thus, this Center is designed to yield patentable new technology and will provide visibility in the field of bioengineering, attracting investment and industry.

This Center has received more than $12 million in federal research grants. This includes National Insitutes of Health (NIH) funding for one of only ten National Heart Lung and Blood Institute Proteomics Centers in the country.

Development of microfluidic devices for proteomic analysis by this Center has led to a new collaboration with The Citadel. Also, a new technology development in mass spectrometry for proteomic analysis in the form of a new dual mode ion source has led to an additional NIH grant. This Center has a partnership with the U.S. Department of Energy Molecular Foundry at the Lawrence Berkeley National laboratory to develop a new type of microfluidic valve based upon a nanostructured polymer for use in proteomic analysis devices.

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