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Inflammation and Fibrosis

Center of Economic Excellence



Award Amount

$5 million

External Funding Above Match


Research Focus

Develop new therapies and education programs for inflammatory and fibrosing rheumatic diseases, such as lupus, scleroderma, and rheumatoid arthritis.

University Partner

Medical University of South Carolina (MUSC)

Private Sector Partner

Multiple Industry Partners

The Center is focused on developing new therapies for inflammatory and fibrosing conditions, which are a major cause of chronic illness in South Carolina and the United States. Fibrosing conditions occur when organs or tissues develop excessive fibrous tissue, which can interfere with the normal function of the organ. Examples of diseases in which inflammation or fibrosis play a prominent role include lupus, cystic fibrosis and scleroderma.

The commercialization of treatments developed by the Center could improve the lives of people afflicted with these debilitating chronic diseases as well as lead to start-up companies and new jobs in South Carolina.

The Medical University of South Carolina has a world-class research group in this field. Dr. Richard Silver is an internationally renowned expert in the study and treatment of scleroderma, while Dr. Gary Gilkerson is widely known for his work with systemic lupus erythematosis. 

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