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Besim Ogretmen, PhD

Endowed Professor of Lipidomics & Drug Discovery

Lipidomics Center of Economic Excellence

  •  Eminent Scholar, Department of Biochemistry & Molecular Biology, Medical University of South Carolina.

  • Leader in the field of lipid signaling and pathobiology with an established NIH-funded research program.

  • His laboratory has made several significant contributions to determine lipid-regulated cell death and cancer therapeutics at a mechanistic level.

  • Selected as one of the“NextGenerationofLipidStars”for special issue of the journal Archives of Biochemistry and Biophysics.

  •  Postdoctoral Studies, Hematology/Oncology, University of Chicago

  • PhD, Molecular Biology, Illinois Institute of Technology

Dr. Ogretmen joined the faculty in the Department of Biochemistry and Molecular Biology at MUSC in 1999 as a Research Assistant Professor and was quickly promoted to his current position of Professor and Eminent Scholar in 2012. In addition to his research and educational duties, Dr. Ogretmen has been instrumental in maintaining and advancing “lipidomics research” at MUSC. Dr. Ogretmen has been the Principal Investigator (PI) and Director of the Center of Biomedical Research Excellence (COBRE) in Lipidomics and Pathobiology at MUSC since 2012. He is also the Program Leader of the Lipid Signaling in Cancer program at the Hollings Cancer Center.

Dr. Ogretmen is currently the PI on three R01 grants from NIH. He has also spearheaded translational research at the Hollings Cancer Center, particularly in his studies with human head and neck, and lung cancers. Dr. Ogretmen and the members of the lipid group at the Hollings Cancer Center have initiated phase I/II clinical trials to target sphingolipid metabolism and signaling for the treatment of patients with advanced solid tumors.

He has published over 85 manuscripts in top-tiered journals such as EMBO Molecular Medicine, Journal of Biological Chemistry, Clinical Cancer Research, and a highly acclaimed review in Nature Reviews Cancer. He is an active member of the American Society of Biochemistry and Molecular Biology, the American Association for the Advancement of Science and the American Association for Cancer Research.

HCC Researcher Profile

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