Regenerative Medicine

Center of Economic Excellence

Inception

2004

Award Amount

$5 million

Extramural Research Funding

$48.6 Million

University Partner

Medical University of South Carolina (MUSC)
Clemson University
University of South Carolina

Private Sector Partner

Health Sciences South Carolina
BlueCross BlueShield of South Carolina Foundation

Regenerative medicine is the regeneration of tissue and organs for the purpose of repairing, replacing, and maintaining organ function. The Regenerative Medicine Center is a collaboration of the Medical University of South Carolina (MUSC), Clemson University and the University of South Carolina. It combines statewide expertise in developmental biology, adult stem cell technology and tissue engineering. The Center’s goals include:

• Fostering basic research in genetics, proteogenomics, developmental biology, cell biology, and physiology of stem cells.
• Translating basic research into novel therapies for genetic and degenerative disorders.
• Collaborating with the private sector to develop business innovation research grants that can lead to partnerships with the business community and the U.S. government.
• Establishing pre-doctoral and postdoctoral training programs in stem cell technology, developmental biology, biomaterials, and tissue engineering.

The most significant scientific accomplishments thus far for this Center are in the field of bioprinting, the assembly of living 3D human tissues and organs using rapid prototyping technology. In addition, advances in the areas of bioengineering, wound healing, vascular biology, orthopedic materials science, and cardiac development have led to an effort to construct a biofabricated blood vessel network.

The Center has research funding for areas such as cardiac tissue engineering, implanted-associated infection and battlefield skeletal injury. This Center will play a major role in the $20 million statewide National Science Foundation grant awarded in July 2009 for tissue and organ biofabrication.

Two research contract partnerships have been established with Synthes USA. A start-up company, FirstString, was created in 2006, which features new wound repair technology; it has generated revenue in excess of $1.2 million.