Molecular Proteomics in Cardiovascular Disease and Prevention Center of Economic Excellence Endowed Chairs

Actively Recruiting
Tourville Endowed Chair
in Cardiovascular Imaging for Diagnosis and Prevention Medical 
University of South Carolina

Actively Recruiting
Volpe Endowed Chair
in Cardiovascular Biomarker Development for Diagnosis and Prevention
Medical University of South Carolina (MUSC)

The Center for Molecular Proteomics in
Cardiovascular Disease and Prevention is
funded by Health Sciences South
Carolina, a statewide biomedical
collaborative consisting of Clemson
University,  Medical University of South Carolina,
University of South Carolina, Greenville
Hospital System, Palmetto Health, and
Spartanburg Regional Healthcare System. More>

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Molecular Proteomics in Cardiovascular Disease and Prevention

Center of Economic Excellence

Inception

2006

Award Amount

$5 million

Extramural Research Funding

$1.5 Million

University Partner

Medical University of South Carolina (MUSC)

Private Sector Partner

Health Sciences South Carolina

This Center advances cardiovascular prevention and treatment bench science into clinical bedside care. This Center’s goals include:

  • Developing measurement systems to detect early heart failure indicators.
  • Relating diagnostic protein signatures to clinical outcomes.
  • Developing therapeutic management strategies.
  • Creating a statewide network to develop, test, and improve clinical care of heart failure.
  • Transferring technology into new South Carolina industries.

The Center maintains a statewide network of five primary, separate care locations to participate and be linked by a central bioinformatics core. This core will allow patients who currently suffer or are at risk for cardiovascular disease from across the state to be screened. In 2009, plasma screening was conducted for 450 patients. Through this screening, 16 plasma proteins were analyzed and a specific biomarker portfolio was created for the diagnosis and prediction of left ventricular hypertrophy and diastolic heart failure.